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Suppression of MAP kinases inhibits microglial activation and attenuates neuronal cell death induced by alpha-synuclein protofibrils.
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Isolation and characterization of cells with neurogenic potential from adult skeletal muscle.
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In vivo imaging of synaptic SV2A protein density in healthy and striatal-lesioned rats with [11C]UCB-J PET.
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PET imaging reveals early and progressive dopaminergic deficits after intra-striatal injection of preformed alpha-synuclein fibrils in rats.
Neurobiology of Disease,
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Bradykinesia and postural instability in a model of prodromal synucleinopathy with α-synuclein aggregation initiated in the gigantocellular nuclei.
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Neuroinflammation and Immune Changes in Prodromal Parkinson’s Disease and Other Synucleinopathies.
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The immune system in Parkinson's disease: what we know so far.
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Decreased mRNA expression of key markers of the nigrostriatal dopaminergic system following vitamin E deficiency in rat.
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Neuronal differentiation of stem cells isolated from adult muscle.
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Semichronic inhibition of glutathione reductase promotes oxidative damage to proteins and induces both transcription and translation of tyrosine hydroxylase in the nigrostriatal system. Free Radic. Res.,
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Increased activity and expression of tyrosine hydroxylase in the rat substantia nigra after chronic treatment with nomifensine.
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Less induced 1-methyl-4-phenylpyridinium ion neurotoxicity on striatal slicesfrom guinea-pigs fed with a vitamin C-deficient diet.
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Progressive striatonigral degeneration in a transgenic mouse model of multiple system atrophy: translational implications for interventional therapies.
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Early synaptic dysfunction induced by α-synuclein in a rat model of Parkinson's disease.
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CD4 T cells react to local increase of α-synuclein in a pathology-associated variant-dependent manner and modify brain microglia in absence of brain pathology.
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Alterations in Blood Monocyte Functions in Parkinson's Disease.
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Molecular properties and diagnostic potential of monoclonal antibodies targeting cytotoxic α-synuclein oligomers.
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Nanobodies raised against the cytotoxic α-synuclein oligomer are oligomer-specific and promote its cellular uptake.
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Transplantation of multipotent cells extracted from adult skeletal muscles into the adult subventricular zone.
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Enhanced production of mesencephalic dopaminergic neurons from lineage-restricted human undifferentiated stem cells.
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Spatial transcriptomics reveals the molecular signatures of prodromal and advanced α-synucleinopathy.
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Changes in CD163+, CD11b+, and CCR2+ peripheral monocytes relate to Parkinson's disease and cognition.
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Impact of aging on animal models of Parkinson´s disease.
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Lack of functional STING modulates immunity but does not protect dopaminergic neurons in the alpha-synuclein pre-formed fibrils Parkinson's disease mouse model.
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Size-Selective Phagocytic Clearance of Fibrillar α-Synuclein through Conformational Activation of Complement Receptor 4.
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Amyloid-β aggregates activate peripheral monocytes in mild cognitive impairment.
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Allelic difference in Mhc2ta confers altered microglial activation and susceptibility to α-synuclein-induced dopaminergic neurodegeneration.
Neurobiology of Disease,
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