Christiansen, J. R., Olesen, M. N., Otzen, D. E., Romero-Ramos, M. & Sanchez-Guajardo, V. (2016).
α-Synuclein vaccination modulates regulatory T cell activation and microglia in the absence of brain pathology.
Journal of Neuroinflammation,
13(1), Article 74.
https://doi.org/10.1186/s12974-016-0532-8
Stokholm, K., Thomsen, M. B., Phan, J. A., Møller, L. K.
, Bay-Richter, C., Christiansen, S. H., Woldbye, D. P. D.
, Romero-Ramos, M. & Landau, A. M. (2021).
α-Synuclein Overexpression Increases Dopamine D2/3 Receptor Binding and Immune Activation in a Model of Early Parkinson’s Disease.
Biomedicines,
9(12), Article 1876.
https://doi.org/10.3390/biomedicines9121876
Febbraro, F., Giorgi, M., Caldarola, S., Loreni, F.
& Romero-Ramos, M. (2012).
α-Synuclein expression is modulated at the translational level by iron.
NeuroReport,
23(9), 576-80.
https://doi.org/10.1097/WNR.0b013e328354a1f0
Mignon, L., Vourc'h, P.
, Romero-Ramos, M., Osztermann, P., Young, HE., Lucas, PA. & Chesselet, MF. (2005).
Transplantation of multipotent cells extracted from adult skeletal muscles into the adult subventricular zone.
J. Comp. Neurol.,
491(2).
Bøttger, P., Tracz, Z., Pelc, M.
, Albertsen, M., Strandbygård, D. J., Romero-Ramos, M. & Lykke-Andersen, K. (2008).
Transgenic mouse models for two inherited neuronal diseases. Poster session presented at 12th International ATPase Conference, Aarhus, Denmark.
Roodveldt, C., Bernardino, L., Oztop-Cakmak, O., Dragic, M., Fladmark, K. E., Ertan, S., Aktas, B., Pita, C., Ciglar, L., Garraux, G., Williams-Gray, C., Pacheco, R.
& Romero-Ramos, M. (2024).
The immune system in Parkinson's disease: what we know so far.
Brain,
147(10), 3306-3324.
https://doi.org/10.1093/brain/awae177Ding, X., Lai, X., Klaestrup, I. H., Jensen, S. R. N., Nielsen, M. M., Thorsen, K., Romero-Ramos, M., Luo, Y., Lin, L., Reinert, L. S. & Paludan, S. R. (2025).
Temporally resolved single-cell RNA sequencing reveals protective and pathological responses during herpes simplex virus CNS infection.
Journal of Neuroinflammation,
22(1), Article 146.
https://doi.org/10.1186/s12974-025-03471-x
Wilms, H., Rosenstiel, P.
, Romero-Ramos, M., Arlt, A., Schäfer, H., Seegert, D., Odoy, S., Claasen, JH., Holzknecht, C., Brandenburg, LO., Deuschl, G., Schreiber, S., Kirik, D. & Lucius, R. (2009).
Suppression of MAP kinases inhibits microglial activation and attenuates neuronal cell death induced by alpha-synuclein protofibrils.
International Journal of Immunopathology and Pharmacology,
22(4), 897-909.
Lin, L., Jensen, N. M., Delaidelli, A.
, Ferreira, S. A., Yarmahmoudi, F., Sorensen, P. H.
, Romero-Ramos, M., Jensen, P. H., Mackenzie, I. R.
, Nyengaard, J. R. & Jan, A. (2026).
Spatial transcriptomics reveals the molecular signatures of prodromal and advanced α-synucleinopathy.
iScience,
29(3), Article 114845.
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Nissen, S. K., Ferreira, S. A., Nielsen, M. C., Schulte, C.
, Shrivastava, K., Hennig, D.
, Etzerodt, A., Graversen, J. H., Berg, D., Maetzler, W., Panhelainen, A.
, Møller, H. J., Brockmann, K.
& Romero-Ramos, M. (2021).
Soluble CD163 Changes Indicate Monocyte Association With Cognitive Deficits in Parkinson's Disease.
Movement Disorders,
36(4), 963-976.
https://doi.org/10.1002/mds.28424
Juul-Madsen, K., Qvist, P., Bendtsen, K. L., Langkilde, A. E., Vestergaard, B.
, Howard, K., Dehesa-Etxebeste, M.
, Paludan, S. R., Andersen, G. R., Jensen, P. H., Otzen, D. E., Romero-Ramos, M. & Vorup-Jensen, T. (2020).
Size-Selective Phagocytic Clearance of Fibrillar α-Synuclein through Conformational Activation of Complement Receptor 4.
Journal of Immunology,
204(5), 1345-1361.
https://doi.org/10.4049/jimmunol.1900494
Almeida Ferreira, S. R., Li, C.
, Klæstrup, I. H., Vitic, Z., Rasmussen, R. K., Kirkegaard, A., Toft, G. U., Betzer, C., Svendsen, P., Jensen, P. H., Luo, Y., Etzerodt, A., Moestrup, S. K. & Romero-Ramos, M. (2023).
Sex-dimorphic neuroprotective effect of CD163 in an α-synuclein mouse model of Parkinson's disease.
npj Parkinson's Disease ,
9(1), 164. Article 164.
https://doi.org/10.1038/s41531-023-00606-w
Febbraro, F., Sahin, G., Farran, A., Soares, S.
, Jensen, P. H., Kirik, D.
& Romero-Ramos, M. (2013).
Ser129D mutant alpha-Synuclein induces earlier Motor Dysfunction while S129A results in distinctive pathology in a rat model of Parkinson's Disease.
Neurobiology of Disease,
56, 47-58.
https://doi.org/10.1016/j.nbd.2013.03.014
Romero-Ramos, M., Venero, JL., Garcia-Rodriguez, S., Ayala, A., Machado, A. & Cano, J. (2003).
Semichronic inhibition of glutathione reductase promotes oxidative damage to proteins and induces both transcription and translation of tyrosine hydroxylase in the nigrostriatal system. Free Radic. Res.,
37(9).
Refolo, V., Bez, F., Polissidis, A., Kuzdas-Wood, D., Sturm, E., Kamaratou, M., Poewe, W., Stefanis, L., Angela Cenci, M.
, Romero-Ramos, M., Wenning, G. K. & Stefanova, N. (2018).
Progressive striatonigral degeneration in a transgenic mouse model of multiple system atrophy: translational implications for interventional therapies.
Acta Neuropathologica Communications,
6(1), 2.
https://doi.org/10.1186/s40478-017-0504-y
Thomsen, M. B., Ferreira, S. A., Schacht, A. C., Jacobsen, J., Simonsen, M., Betzer, C., Jensen, P. H., Brooks, D. J., Landau, A. M. & Romero-Ramos, M. (2021).
PET imaging reveals early and progressive dopaminergic deficits after intra-striatal injection of preformed alpha-synuclein fibrils in rats.
Neurobiology of Disease,
149, Article 105229.
https://doi.org/10.1016/j.nbd.2020.105229
Christiansen, J. R., Ferreira, S. A., Szymkowski, D. E., Jakobsson, J., Tansey, M. G.
& Romero-Ramos, M. (2025).
Peripherally administered TNF inhibitor is not protective against α-synuclein-induced dopaminergic neuronal death in rats.
Neurobiology of Disease,
206, Article 106803.
https://doi.org/10.1016/j.nbd.2025.106803
Romero-Ramos, M., Vourc'h, P., Young, HE., Lucas, PA., Wu, Y., Chivatakarn, O., Zaman, R., Dunkelman, N., el-Kalay, MA. & Chesselet, MF. (2002).
Neuronal differentiation of stem cells isolated from adult muscle.
J Neurosci Res.,
69(6).
Terkelsen, M. H., Klæstrup, I. H., Hvingelby, V., Lauritsen, J., Pavese, N. & Romero-Ramos, M. (2022).
Neuroinflammation and Immune Changes in Prodromal Parkinson’s Disease and Other Synucleinopathies.
Journal of Parkinson's Disease,
12(s1), S149-S163.
https://doi.org/10.3233/JPD-223245
Nielsen, J., Pedersen, J. N., Kleijwegt, G.
, Nowak, J. S., Nami, F., Johansen, C., Sassetti, E.
, Berg, B. B., Lyngsø, N. M., Brøchner, B. H., Holm Carlson, J.
, Simonsen, A. J., Pallisgaard Olsen, W., Simonsen, B. W., Mikkelsen, J. H., Sereika-Bejder, V.
, Lauritsen, J. A., Merrild, K. F., Malle, M. G. ... Otzen, D. E. (2025).
Nanobodies raised against the cytotoxic α-synuclein oligomer are oligomer-specific and promote its cellular uptake.
npj biosensing,
2, Article 23.
https://doi.org/10.1038/s44328-025-00042-1
Ferreira, N., Gram, H., Sorrentino, Z. A.
, Gregersen, E., Schmidt, S. I.
, Reimer, L., Betzer, C., Perez-Gozalbo, C.
, Beltoja, M., Nagaraj, M., Wang, J., Nowak, J. S., Dong, M., Willén, K., Cholak, E.
, Bjerregaard-Andersen, K., Mendez, N., Rabadia, P., Shahnawaz, M.
... Jensen, P. H. (2021).
Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential.
Acta Neuropathologica,
142, 87-115.
https://doi.org/10.1007/s00401-021-02316-0
Farmen, K., Nissen, S. K., Stokholm, M. G., Iranzo, A.
, Østergaard, K., Serradell, M.
, Otto, M., Svendsen, K. B., Garrido, A., Vilas, D.
, Borghammer, P., Santamaria, J.
, Møller, A., Gaig, C.
, Brooks, D. J., Tolosa, E.
, Pavese, N. & Romero-Ramos, M. (2021).
Monocyte markers correlate with immune and neuronal brain changes in REM sleep behavior disorder.
Proceedings of the National Academy of Sciences (PNAS),
118(10), Article e2020858118.
https://doi.org/10.1073/pnas.2020858118
Nielsen, J., Lauritsen, J., Pedersen, J. N., Nowak, J. S., Bendtsen, M. K., Kleijwegt, G., Lusser, K.
, Pitarch, L. C., Moreno, J. V., Schneider, M. M., Krainer, G., Goksøyr, L., Khalifé, P., Kaalund, S. S., Aznar, S.
, Kjærgaard, M., Sereikaité, V., Strømgaard, K., Knowles, T. P. J.
... Otzen, D. E. (2024).
Molecular properties and diagnostic potential of monoclonal antibodies targeting cytotoxic α-synuclein oligomers.
npj Parkinson's Disease ,
10(1), Article 139.
https://doi.org/10.1038/s41531-024-00747-6
Eslamboli, A.
, Romero-Ramos, M., Burger, C., Bjorklund, T., Muzyczka, N., Mandel, R. J., Baker, H., Ridley, R. M. & Kirik, D. (2007).
Long-term overexpression of alpha-synuclein in primates ventral midbrain leads to motor behavioral deficits.
Brain,
130(3), 799-815.
Revuelta, M.
, Romero-Ramos, M., Venero, JL., Millan, F. & Machado, A. (1997).
Less induced 1-methyl-4-phenylpyridinium ion neurotoxicity on striatal slicesfrom guinea-pigs fed with a vitamin C-deficient diet.
Neuroscience,
77(1), 167-174.
Klæstrup, I. H., Reinert, L. S., Ferreira, S. A., Lauritsen, J., Toft, G. U., Gram, H., Jensen, P. H., Paludan, S. R. & Romero-Ramos, M. (2026).
Lack of functional STING modulates immunity but does not protect dopaminergic neurons in the alpha-synuclein pre-formed fibrils Parkinson's disease mouse model.
npj Parkinson's Disease ,
12(1), Article 17. Advance online publication.
https://doi.org/10.1038/s41531-025-01228-0
Vourc'h, P.
, Romero-Ramos, M., Chivatakarn, O., Young, HE., Lucas, PA., Wu, Y., el-Kalay, MA. & Chesselet, MF. (2004).
Isolation and characterization of cells with neurogenic potential from adult skeletal muscle.
Biochem. Biophys. Res. Commun.,
317(3).
Thomsen, M., Jacobsen, J., Lillethorup, T. P., Schacht, A. C., Simonsen, M. I. T., Romero-Ramos, M., Brooks, D. J. & Landau, A. (2021).
In vivo imaging of synaptic SV2A protein density in healthy and striatal-lesioned rats with [11C]UCB-J PET.
Journal of Cerebral Blood Flow and Metabolism,
41(4), 819-830.
https://doi.org/10.1177/0271678X20931140
Fonager, S. V., Winther, G., Wittenborn, T. R., Jensen, L., Fahlquist-Hagert, C., Hansen, L. A., Füchtbauer, E.-M., Romero-Ramos, M. & Degn, S. E. (2022).
Increased maternofoetal transfer of antibodies in a murine model of systemic lupus erythematosus, but no immune activation and neuroimmune sequelae in offspring.
Journal of Neuroimmunology,
370, Article 577927.
https://doi.org/10.1016/j.jneuroim.2022.577927
Rodríguez-Gómez, JA.
, Romero-Ramos, M., Vizuete, ML., Venero, JL., Cano, J. & Machado, A. (1997).
Increased activity and expression of tyrosine hydroxylase in the rat substantia nigra after chronic treatment with nomifensine.
Mol. Pharmacol.,
52(4).
Klæstrup, I. H., Pedersen, M. K. J., Holm, K. L., Alstrup, A. K. O., Romero-Ramos, M., Borghammer, P. & Van Den Berge, N. (2022).
Impact of aging on animal models of Parkinson´s disease.
Frontiers in Aging Neuroscience,
14, Article 909273.
https://doi.org/10.3389/fnagi.2022.909273
Gugu, M., Acharya, S., Pira, D., Poletti, S., di Flora, A., Saksida, T., Pilipenko, V.
, Romero-Ramos, M., Marino, F., Muñoz Delgado, L., Nikolovski, N., Gursoy Ozdemir, Y., Lawson, D., Comi, C. & Figueira, I. (2025).
IMMUnity Unveiled: A Translational NETwork for tackling PARKinson's Disease – IMMUPARKNET.
Open Research Europe,
4, Article 119.
https://doi.org/10.12688/openreseurope.17547.2